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Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Ä¢¹½ÊÓƵ researchers have discovered.

The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Ä¢¹½ÊÓƵ researchers demonstrate.

Ä¢¹½ÊÓƵ Medical Center is attracting international attention for its proposal to repurpose existing drugs for new uses in ways that can dramatically improve access to medicines by billions of people throughout the world.

A cellular RNA quality control mechanism was known to restrict replication of RNA viruses. Ä¢¹½ÊÓƵ researchers have discovered it is also antiviral against DNA viruses.

Katherine Amidon, a PhD student in the Department of Biological Sciences at Ä¢¹½ÊÓƵ, has been selected as the 2020 Ä¢¹½ÊÓƵ Prize Student Scholar.

Researchers at Ä¢¹½ÊÓƵ Medical Center have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy.

Based on positive results in preclinical studies reported today, potently neutralizing antibodies identified by researchers at Ä¢¹½ÊÓƵ Medical Center are showing promise as a potential therapy for preventing and treating COVID-19.

An experimental coronavirus vaccine stimulated robust immune responses against SARS-CoV-2, the virus that causes COVID-19, and raised no serious safety concerns in an early-stage clinical trial.

Ä¢¹½ÊÓƵ researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction.

Ä¢¹½ÊÓƵ immunologists have discovered that the protein Nur77 is part of a control mechanism that guards against autoimmunity in natural killer T cells.

This week researchers at Ä¢¹½ÊÓƵ Medical Center (VUMC), the University of North Carolina at Chapel Hill and Gilead Sciences reported that remdesivir potently inhibited SARS-CoV-2, the virus which causes COVID-19, in human lung cell cultures and that it improved lung function in mice infected with the virus.

Bacterial invasion of vaginal cells sets up a protective niche and a reservoir for recurrent urinary tract infections, Ä¢¹½ÊÓƵ researchers demonstrated.

The Ä¢¹½ÊÓƵ Institute for Infection, Immunology and Inflammation (VI4) recently moved into its new research and administrative home.

Ä¢¹½ÊÓƵ cell biologists are defining the factors that help beta cells in the pancreas stay healthy, secrete insulin and prevent diabetes initiation and progression.

Sunil Kripalani, MD, MSc, professor of Medicine at Ä¢¹½ÊÓƵ Medical Center, has been appointed director of the Ä¢¹½ÊÓƵ Center for Health Services Research.

Scientists at Ä¢¹½ÊÓƵ Medical Center and the Translational Genomics Research Institute (TGen) in Phoenix, Arizona, have discovered previously unreported genetic and cellular changes that occur in the lungs of people with pulmonary fibrosis (PF).

Researchers at Ä¢¹½ÊÓƵ Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.

With the aid of a $75 million, five-year grant renewal, the Electronic Medical Records and Genomics Network (eMERGE) will venture beyond its current focus on monogenic disease to scoring research participants relative risk for complex heritable diseases such as cardiovascular disease, chronic kidney disease and type 2 diabetes.

The Ä¢¹½ÊÓƵ Institute for Clinical and Translational Research (VICTR), which provides comprehensive support for clinical and translational research at Ä¢¹½ÊÓƵ Medical Center (VUMC), has been named Administrative Coordinating Center (ACC) of a national effort to streamline the research response to life-threatening lung and heart problems caused by COVID-19.

People with inoperable anal cancer treated with carboplatin-paclitaxel had fewer complications and lived longer than those who received another chemotherapy that has been more often administered.